Brugada Syndrome

An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Also Known As:

Brugada ECG Pattern; Brugada Syndrome 1; Brugada Type ECG Pattern; Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome; Sudden Unexplained Death Syndrome; Sudden Unexplained Nocturnal Death Syndrome; Sudden Unexplained Nocturnal Death Syndrome (SUNDS); ECG Pattern, Brugada

Cardiovascular Diseases: 94258
- Heart Diseases: 26486
  - Cardiac Arrhythmias: 21201
    - Brugada Syndrome: 1294
  - Cardiac Conduction System Disease: 95
    - Brugada Syndrome: 1294
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 960
- Inborn Genetic Diseases: 12342
  - Brugada Syndrome: 1294

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Disease

Drug/Important Bio-Agent (IBA)